Slc43a2^{Gt(258C1)Cmhd}
Gene trapped Allele Detail

Summary

• Symbol: Slc43a2^{Gt(258C1)Cmhd}
• Name: solute carrier family 43, member 2; gene trap 258C1, Centre for Modeling Human Disease
• MGI ID: MGI:4968311
• Synonyms: Lat4^-
• Gene: Slc43a2 Location: Chr11:75422520-75468401 bp, + strand Genetic Position: Chr11, 45.92 cM
• Alliance: Slc43a2^{Gt(258C1)Cmhd} page

Mutation origin

• Mutant Cell Line: 258C1
• Germline Transmission: Earliest citation of germline transmission: J:237439
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: UPA
• Mutation details: A UPA gene trap vector inserted into the sixth intron of the gene. This mutation is predicted result in the production of a truncated transcript. Immunofluorescence experiments of the small intestine and kidney proximal tubule of 3-day-old homozygous mutant pups showed that no expression is detected in the small intestine and kidney proximal tubule compared to control littermates. (J:237439)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  CMHD-GT_258C1-3	ED562654 ; (MGI Seq Detail)	3' RACE	Chr11:75453600-75457853 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  9 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc43a2 Mutation: 28 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)