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Rnf168Gt(405F11)Cmhd
Gene trapped Allele Detail
Summary
Symbol: Rnf168Gt(405F11)Cmhd
Name: ring finger protein 168; gene trap 405F11, Centre for Modeling Human Disease
MGI ID: MGI:4962718
Gene: Rnf168  Location: Chr16:32096277-32120252 bp, + strand  Genetic Position: Chr16, 22.51 cM, cytoband B2
Alliance: Rnf168Gt(405F11)Cmhd page
Mutation
origin
Mutant Cell Line:  405F11
Germline Transmission:  Earliest citation of germline transmission: J:198260
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: GepNMDi3
 
Mutation detailsThe gene trap vector inserted upstream of exon 6. Western blot analysis confirmed the absence of protein expression in the mouse embryonic fibroblasts and splenocytes. (J:198260)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Rnf168Gt(405F11)Cmhd
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rnf168 Mutation:  73 strains or lines available
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory