Blk^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Blk^{tm1(KOMP)Vlcg}
• Name: B lymphoid kinase; targeted mutation 1, Velocigene
• MGI ID: MGI:4951259
• Gene: Blk Location: Chr14:63610285-63654486 bp, - strand Genetic Position: Chr14, 33.25 cM
• Alliance: Blk^{tm1(KOMP)Vlcg} page
• IMPC: Blk gene page

Mutation origin

• Mutant Cell Lines: 15739A-C5, 15739A-F4, 15739A-G8, 15739A-H1, 15739A-H2, 15739A-H8
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 14534bp between positions 63610739-63625272 of Chromosome 14 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Blk Mutation: 27 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)