Fcrlb^tm2(KOMP)Mbp
Targeted Allele Detail

Summary

• Symbol: Fcrlb^tm2(KOMP)Mbp
• Name: Fc receptor-like B; targeted mutation 2, Mouse Biology Program, UC Davis
• MGI ID: MGI:4950123
• Gene: Fcrlb Location: Chr1:170734842-170740510 bp, - strand Genetic Position: Chr1, 77.56 cM
• IMPC: Fcrlb gene page

Mutation origin

• Mutant Cell Lines: DEPD00552_1_A01, DEPD00552_1_A03, DEPD00552_1_B02, DEPD00552_1_D01, DEPD00552_1_D02, DEPD00552_1_D03, DEPD00552_1_E02, DEPD00552_1_F01, DEPD00552_1_F02, DEPD00552_1_G03
• Germline Transmission: Unknown
• Parent Cell Line: JM8 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 5150 starting at position 170734840 and ending at position 170739990 of Chromosome 1 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157064)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fcrlb Mutation: 24 strains or lines available

References

• Original: J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010
• All: 1 reference(s)