H2-T23tm1(KOMP)Mbp
Targeted Allele Detail
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Symbol: |
H2-T23tm1(KOMP)Mbp |
Name: |
histocompatibility 2, T region locus 23; targeted mutation 1, Mouse Biology Program, UC Davis |
MGI ID: |
MGI:4950115 |
Gene: |
H2-T23 Location: Chr17:36340869-36343593 bp, - strand Genetic Position: Chr17, 18.86 cM
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IMPC: |
H2-T23 gene page |
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Mutant Cell Lines: |
DEPD00555_5_A01, DEPD00555_5_A04, DEPD00555_5_B01, DEPD00555_5_B03, DEPD00555_5_C01, DEPD00555_5_C02, DEPD00555_5_C03, DEPD00555_5_D02, DEPD00555_5_D03, DEPD00555_5_D04, DEPD00555_5_E01, DEPD00555_5_E03, DEPD00555_5_E04, DEPD00555_5_F02, DEPD00555_5_F03, DEPD00555_5_G02, DEPD00555_5_G04, DEPD00555_5_H02, DEPD00555_5_H03, DEPD00555_5_H04 |
Germline Transmission: |
Unknown
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 1992 starting at position 36340863 and ending at position 36342855 of Chromosome 17 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157064)
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Original: |
J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010; |
All: |
1 reference(s) |
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