Pkd1l1^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Pkd1l1^tm1Lex
• Name: polycystic kidney disease 1 like 1; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:4949891
• Gene: Pkd1l1 Location: Chr11:8782025-8924365 bp, - strand Genetic Position: Chr11, 5.57 cM, cytoband A2
• Alliance: Pkd1l1^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171184
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 10, 11, and 12 were replaced with a lacZ reporter and a neomycin selection cassette. (J:171184)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Pkd1l1 Mutation: 155 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:171184 Vogel P, et al., Situs inversus in Dpcd/Poll-/-, Nme7-/- , and Pkd1l1-/- mice. Vet Pathol. 2010 Jan;47(1):120-31
• All: 3 reference(s)