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Kcnu1tm1.2Clin
Targeted Allele Detail
Nomenclature
Symbol: Kcnu1tm1.2Clin
Name: potassium channel, subfamily U, member 1; targeted mutation 1.2, Christopher J Lingle
MGI ID: MGI:4949763
Gene: Kcnu1  Location: Chr8:25849623-25937933 bp, + strand  Genetic Position: Chr8, 14.17 cM, cytoband A3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171225
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination removed exon 27, the EGFP, and the neo cassette. The absence of protein expression was confirmed by western blot analysis on testes extracts. (J:171225)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnu1 Mutation:  30 strains or lines available
Notes
ES cell line = SF29 (strain of origin not provided in original reference)
References
Original:  J:171225 Zeng XH, et al., Deletion of the Slo3 gene abolishes alkalization-activated K+ current in mouse spermatozoa. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5879-84
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory