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Targeted Allele Detail
Symbol: Kif5ctm2Gsn
Name: kinesin family member 5C; targeted mutation 2, Lawrence S B Goldstein
MGI ID: MGI:4949203
Synonyms: Kinesin-1C-
Gene: Kif5c  Location: Chr2:49619298-49774778 bp, + strand  Genetic Position: Chr2, 28.68 cM, cytoband C
Germline Transmission:  Earliest citation of germline transmission: J:170887
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neo cassette replaced two exons, which code for amino acid 132 to the first two nucleotides of amino acid 196. The absence of protein expression was confirmed by western blot analysis of brain lysates. (J:170887)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kif5c Mutation:  26 strains or lines available
Original:  J:170887 Encalada SE, et al., Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles. Cell. 2011 Feb 18;144(4):551-65
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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