Tg(AMELX*)29Gibs
Transgene Detail

Summary

• Symbol: Tg(AMELX*)29Gibs
• Name: transgene insertion 29, Carolyn Gibson
• MGI ID: MGI:4948682
• Synonyms: Tg(AMELX*CT)29Gibs, TgCTRNC29
• Transgene: Tg(AMELX*)29Gibs Location: unknown
• Alliance: Tg(AMELX*)29Gibs page

Transgene origin

• Strain of Origin: C57BL/6 and SJL

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(AMELX*)29Gibs expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  AMELX (265)

  Amelx

  (MGI:88005)

• Mutation details: The transgene expresses the human cDNA lacking the sequence coding for the C-terminal 13 amino acids. Five lines were generated, including lines 2 (2 copies), 18 (28 copies), and 29 (2 copies). (J:170228)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:170228 Pugach MK, et al., The amelogenin C-terminus is required for enamel development. J Dent Res. 2010 Feb;89(2):165-9
• All: 2 reference(s)