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Oprm1tm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Oprm1tm1Lex
Name: opioid receptor, mu 1; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:4948248
Gene: Oprm1  Location: Chr10:6758593-7038209 bp, + strand  Genetic Position: Chr10, 1.85 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:170718
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Exons 2 and 3 were disrupted. (J:170718)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Oprm1 Mutation:  35 strains or lines available
References
Original:  J:170718 Kogel B, et al., The antinociceptive and antihyperalgesic effect of tapentadol is partially retained in OPRM1 (mu-opioid receptor) knockout mice. Neurosci Lett. 2011 Mar 17;491(2):104-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/04/2020
MGI 6.14
The Jackson Laboratory