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Targeted Allele Detail
Symbol: Csrp3tm1.1Rkn
Name: cysteine and glycine-rich protein 3; targeted mutation 1.1, Ralph Knoll
MGI ID: MGI:4947957
Synonyms: MlpW4R
Gene: Csrp3  Location: Chr7:48830398-48848051 bp, - strand  Genetic Position: Chr7, 31.11 cM, cytoband B3
Germline Transmission:  Earliest citation of germline transmission: J:170878
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted
Mutations:    Insertion, Single point mutation
Mutation detailsExon 2 was replaced with one in which a T to C transition results in the amino acid substitution of arginine for tryptophan at position 4 (W4R). A floxed neo cassette inserted downstream of the modified exon 2 was removed by cre-mediated recombination. Reduced protein expression was confirmed by western blot analysis. (J:170878)
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Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Csrp3 Mutation:  1 strain or line available
Original:  J:170878 Knoll R, et al., A common MLP (muscle LIM protein) variant is associated with cardiomyopathy. Circ Res. 2010 Mar 5;106(4):695-704
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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