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Targeted Allele Detail
Symbol: Calr3tm1Osb
Name: calreticulin 3; targeted mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI ID: MGI:4946941
Gene: Calr3  Location: Chr8:72424176-72443870 bp, - strand  Genetic Position: Chr8, 35.08 cM, cytoband C1
Germline Transmission:  Earliest citation of germline transmission: J:170595
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neo cassette replaced most of exons 3 and 4. The absence of protein expression was confirmed by western blot analysis on testis lysates. (J:170595)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Calr3 Mutation:  11 strains or lines available
Original:  J:170595 Ikawa M, et al., Calsperin is a testis-specific chaperone required for sperm fertility. J Biol Chem. 2011 Feb 18;286(7):5639-46
All:  2 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory