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Zbtb7btm1.1Skok
Targeted Allele Detail
Nomenclature
Symbol: Zbtb7btm1.1Skok
Name: zinc finger and BTB domain containing 7B; targeted mutation 1.1, Jane A Skok
MGI ID: MGI:4943529
Synonyms: Zbtb7bhd
Gene: Zbtb7b  Location: Chr3:89377644-89393673 bp, - strand  Genetic Position: Chr3, 39.09 cM, cytoband A1-A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:169841
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Not Specified)
Mutations:    Insertion, Single point mutation
 
Mutation detailsA floxed neo cassette was inserted upstream of the coding region. An A to G transition was inserted into exon 2 (the first coding exon) giving rise to an R389G mutation. Cre-mediated recombination removed the neo cassette. (J:169841)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zbtb7b Mutation:  19 strains or lines available
References
Original:  J:169841 Collins A, et al., RUNX Transcription Factor-Mediated Association of Cd4 and Cd8 Enables Coordinate Gene Regulation. Immunity. 2011 Mar 25;34(3):303-14
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/07/2020
MGI 6.14
The Jackson Laboratory