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Axin1tm1.2Dic
Targeted Allele Detail
Nomenclature
Symbol: Axin1tm1.2Dic
Name: axin 1; targeted mutation 1.2, Di Chen
MGI ID: MGI:4941943
Synonyms: Axin1del
Gene: Axin1  Location: Chr17:26138688-26195811 bp, + strand  Genetic Position: Chr17, 13.07 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:169694
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination removed exon 2. The absence of protein expression was confirmed by western blot analysis on embryo extracts. (J:169694)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Axin1 Mutation:  8 strains or lines available
References
Original:  J:169694 Xie R, et al., Generation of Axin1 conditional mutant mice. Genesis. 2011 Feb;49(2):98-102
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory