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Adora2btm1Msit
Targeted Allele Detail
Nomenclature
Symbol: Adora2btm1Msit
Name: adenosine A2b receptor; targeted mutation 1, Michail Sitkovsky
MGI ID: MGI:4941885
Gene: Adora2b  Location: Chr11:62248984-62266452 bp, + strand  Genetic Position: Chr11, 37.96 cM, cytoband B2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:169155
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. (J:169155)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adora2b Mutation:  5 strains or lines available
References
Original:  J:169155 Belikoff BG, et al., A2B adenosine receptor blockade enhances macrophage-mediated bacterial phagocytosis and improves polymicrobial sepsis survival in mice. J Immunol. 2011 Feb 15;186(4):2444-53
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory