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Ier3tm1Mxw
Targeted Allele Detail
Nomenclature
Symbol: Ier3tm1Mxw
Name: immediate early response 3; targeted mutation 1, Mei X Wu
MGI ID: MGI:4941879
Synonyms: IEX-1 KO
Gene: Ier3  Location: Chr17:36132605-36133803 bp, + strand  Genetic Position: Chr17, 18.7 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:157504
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 1.5 kb region including part of exon 1, all of intron 1 and most of exon 2 was replaced with a lacZ, pgk-neo cassette via homologous recombination. (J:157504)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ier3 Mutation:  8 strains or lines available
References
Original:  J:157504 Akilov OE, et al., Enhanced susceptibility to Leishmania infection in resistant mice in the absence of immediate early response gene X-1. J Immunol. 2009 Dec 15;183(12):7994-8003
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory