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Itpr3tm1.1Rmnc
Targeted Allele Detail
Nomenclature
Symbol: Itpr3tm1.1Rmnc
Name: inositol 1,4,5-triphosphate receptor 3; targeted mutation 1.1, Rocky Mountain Regional Neurological Disorders Center
MGI ID: MGI:4941855
Synonyms: IP3R3tm1(tauGFP), Itpr3tm1.1(Mapt/GFP)Rmnc
Gene: Itpr3  Location: Chr17:27057304-27122223 bp, + strand  Genetic Position: Chr17, 13.68 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:169498
Parent Cell Line:  EC7.1 (ES Cell)
Strain of Origin:  (C57BL/6J x 129X1/SvJ)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a MAPT/GFP fusion, 3 polyadenylation sequences, and a floxed neo cassette. Cre-mediated recombination removed the neo cassette. (J:169498)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Itpr3 Mutation:  43 strains or lines available
Notes
J:169498 author noemenclature for ES cell line: c7.1
References
Original:  J:169498 Hegg CC, et al., Microvillous cells expressing IP3 receptor type 3 in the olfactory epithelium of mice. Eur J Neurosci. 2010 Nov;32(10):1632-45
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory