Cdk5^tm1.2Lht
Targeted Allele Detail

Summary

• Symbol: Cdk5^tm1.2Lht
• Name: cyclin dependent kinase 5; targeted mutation 1.2, Li-Huei Tsai
• MGI ID: MGI:4941830
• Gene: Cdk5 Location: Chr5:24623239-24628528 bp, - strand Genetic Position: Chr5, 11.73 cM, cytoband A3-B1
• Alliance: Cdk5^tm1.2Lht page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:169741
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exons 1 through 5. (J:169741)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdk5 Mutation: 15 strains or lines available

References

• Original: J:169741 Samuels BA, et al., Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK. Neuron. 2007 Dec 6;56(5):823-37
• All: 2 reference(s)