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Dpysl5tm1Gosh
Targeted Allele Detail
Nomenclature
Symbol: Dpysl5tm1Gosh
Name: dihydropyrimidinase-like 5; targeted mutation 1, Yoshio Goshima
MGI ID: MGI:4941238
Gene: Dpysl5  Location: Chr5:30711564-30799369 bp, + strand  Genetic Position: Chr5, 16.8 cM, cytoband B1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:168982
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 through 6 were replaced with an IRES/lacZ/neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:168982)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dpysl5 Mutation:  18 strains or lines available
References
Original:  J:168982 Yamashita N, et al., CRMP5 (Collapsin Response Mediator Protein 5) Regulates Dendritic Development and Synaptic Plasticity in the Cerebellar Purkinje Cells. J Neurosci. 2011 Feb 2;31(5):1773-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory