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Adartm1Olds
Targeted Allele Detail
Nomenclature
Symbol: Adartm1Olds
Name: adenosine deaminase, RNA-specific; targeted mutation 1, Michael B A Oldstone
MGI ID: MGI:4941203
Synonyms: Adar1p150-
Gene: Adar  Location: Chr3:89622329-89660753 bp, + strand  Genetic Position: Chr3, 39.19 cM, cytoband F2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:169014
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Modified isoform(s))
Mutations:    Insertion, Intragenic deletion
    Exon 1a was replaced with a floxed neo cassette. This exon is required for isoform p150. (J:169014)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adar Mutation:  58 strains or lines available
References
Original:  J:169014 Ward SV, et al., RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):331-6
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/27/2022
MGI 6.21
The Jackson Laboratory