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Lrrk1tm1.1Mjff
Targeted Allele Detail
Nomenclature
Symbol: Lrrk1tm1.1Mjff
Name: leucine-rich repeat kinase 1; targeted mutation 1.1, The Michael J Fox Foundation
MGI ID: MGI:4940302
Synonyms: Lrrk1tm1.1Youy
Gene: Lrrk1  Location: Chr7:66226912-66388350 bp, - strand  Genetic Position: Chr7, 35.57 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:169289
Parent Cell Line:  B6-3 (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details A targeting vector replaced exons 24-29 of the leucine-rich repeat kinase 1 (Lrrk1) gene with a loxP-flanked neomycin resistance (neo) cassette. Cre-mediated recombination removed the neo cassette. (J:169289)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Lrrk1 Mutation:  6 strains or lines available
References
Original:  J:169289 Ouyang Y, Direct Data Submission 2011/03/10. MGI Direct Data Submission. 2011;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory