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Tiraptm1.1Pjh
Targeted Allele Detail
Nomenclature
Symbol: Tiraptm1.1Pjh
Name: toll-interleukin 1 receptor (TIR) domain-containing adaptor protein; targeted mutation 1.1, Paul J Hertzog
MGI ID: MGI:4939795
Gene: Tirap  Location: Chr9:35184551-35200291 bp, - strand  Genetic Position: Chr9, 19.99 cM, cytoband A5.3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:168781
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 2 and 3 were flanked by loxP sites. Cre-mediated recombination removed exons 2 and 3. (J:168781)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tirap Mutation:  11 strains or lines available
References
Original:  J:168781 Greenhill CJ, et al., IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3. J Immunol. 2011 Jan 15;186(2):1199-208
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory