Dbi^tm1Smdp
Targeted Allele Detail

Summary

• Symbol: Dbi^tm1Smdp
• Name: diazepam binding inhibitor; targeted mutation 1, Susanne Mandrup
• MGI ID: MGI:4939621
• Synonyms: ACBP^-
• Gene: Dbi Location: Chr1:120041010-120048808 bp, - strand Genetic Position: Chr1, 52.65 cM, cytoband E2
• Alliance: Dbi^tm1Smdp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:168744
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Exon 2 was replaced with a floxed neo cassette. The absence of protein expression was confirmed by western blot analysis on liver extracts. (J:168744)

Generation of the Dbi^tm1Smdp allele

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dbi Mutation: 23 strains or lines available

References

• Original: J:168744 Neess D, et al., Disruption of the Acyl-CoA-binding Protein Gene Delays Hepatic Adaptation to Metabolic Changes at Weaning. J Biol Chem. 2011 Feb 4;286(5):3460-72
• All: 12 reference(s)