Tg(Fos/EGFP)#Brth
Transgene Detail

Summary

• Symbol: Tg(Fos/EGFP)#Brth
• Name: transgene insertion, Alison Barth
• MGI ID: MGI:4938271
• Synonyms: fosGFP
• Transgene: Tg(Fos/EGFP)#Brth Location: unknown
• Alliance: Tg(Fos/EGFP)#Brth page

Transgene origin

• Strain of Origin: (DBA x C57BL/6)F1

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: This transgene contains a fusion of the c-fos promoter and the c-fos coding region, including exons and introns, to the coding region for enhanced green fluorescent protein (EGFP) creating a fosGFP C-terminus fusion protein. The gene for EGFP was fused in frame to the last exon, and the poly(A) tail is derived from the IRES (phosphorylated-internal ribosomal entry site)-EGFP. Four lines were established (lines 1-3, 4-1, 5-1, and 6-1) with slightly different levels of expression in the central nervous system. (J:159440)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:167717 Yassin L, et al., An embedded subnetwork of highly active neurons in the neocortex. Neuron. 2010 Dec 22;68(6):1043-50
• All: 6 reference(s)