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Tg(CAG-Rpgr)mRDefWrght
Transgene Detail
Nomenclature
Symbol: Tg(CAG-Rpgr)mRDefWrght
Name: transgene insertion mRDef, Rachel Wright
MGI ID: MGI:4936750
Synonyms: Rpgrex1-19
Transgene: Tg(CAG-Rpgr)mRDefWrght  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CAG-Rpgr)mRDefWrght expresses 1 gene
 
Mutation detailsThe CAG promoter drives expression of a cDNA encoding exons 1 through 19 with an N-terminus 3x-Myc tag. (J:181417)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:181417 Wright RN, et al., Misexpression of the constitutive Rpgr(ex1-19) variant leads to severe photoreceptor degeneration. Invest Ophthalmol Vis Sci. 2011 Jul;52(8):5189-201
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory