Tlr9^M8Btlr
Chemically induced Allele Detail

Summary

• Symbol: Tlr9^M8Btlr
• Name: toll-like receptor 9; mutation 8, Bruce Beutler
• MGI ID: MGI:4887254
• Synonyms: Meager, Tlr9^D210Y
• Gene: Tlr9 Location: Chr9:106099797-106104075 bp, + strand Genetic Position: Chr9, 57.46 cM
• Alliance: Tlr9^M8Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A to T transversion at position 734 of the Tlr9 transcript (Genbank record NM_031178.2) results in a conversion of an asparagine to a tyrosine at residue 210 in the sixth leucine rich repeat. (J:168138)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tlr9 Mutation: 65 strains or lines available

References

• Original: J:168138 Blasius AL, et al., Record for Meager, updated Feb 09, 2011. MUTAGENETIX (TM), B. Beutler and colleagues, Department of Genetics, The Scripps Research Institute, La Jolla, CA. MGI Direct Data Submission. 2011
• All: 1 reference(s)