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Targeted Allele Detail
Symbol: Hormad1tm1Rajk
Name: HORMA domain containing 1; targeted mutation 1, Aleksandar Rajkovic
MGI ID: MGI:4887242
Gene: Hormad1  Location: Chr3:95559677-95587671 bp, + strand  Genetic Position: Chr3, 40.74 cM, cytoband F2
Germline Transmission:  Earliest citation of germline transmission: J:167522
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 4 and 5 were replaced with a neomycin resistance gene. Small amounts of truncated RNA transcripts were detectable on RT-PCR, and Western blot analysis on testis extracts showed absence of the protein. (J:167522)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hormad1 Mutation:  20 strains or lines available
Original:  J:167522 Shin YH, et al., Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis. PLoS Genet. 2010;6(11):e1001190
All:  2 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory