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Transgene Detail
Symbol: Tg(TCF/Lef1-HIST1H2BB/EGFP)61Hadj
Name: transgene insertion 61, Anna-Katerina Hadjantonakis
MGI ID: MGI:4881498
Synonyms: TCF/Lef:H2B-GFP
Transgene: Tg(TCF/Lef1-HIST1H2BB/EGFP)61Hadj  Location: unknown  
Strain of Origin:  C57BL/6 x 129
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
Mutation detailsThe TCF/Lef:H2B-GFP transgene was designed with six copies of a T cell specific transcription factor/lymphoid enhancer-binding factor 1 (TCF/Lef1) DNA binding site and a heat shock protein 1B (Hspa1b) minimal promoter driving expression of an H2B-EGFP fusion protein (coding sequence for the human HIST1H2BB gene [histone 1 H2bb] followed C-terminally by Enhanced Green Fluorescent Protein gene), followed by a simian virus 40 (SV40) polyadenylation signal. (J:167970)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:167970 Ferrer-Vaquer A, et al., A sensitive and bright single-cell resolution live imaging reporter of Wnt/ss-catenin signaling in the mouse. BMC Dev Biol. 2010;10:121
All:  63 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
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