About   Help   FAQ
Fxntm1.1Pand
Targeted Allele Detail
Nomenclature
Symbol: Fxntm1.1Pand
Name: frataxin; targeted mutation 1.1, Massimo Pandolfo
MGI ID: MGI:4881494
Gene: Fxn  Location: Chr19:24261453-24280586 bp, - strand  Genetic Position: Chr19, 19.39 cM, cytoband C1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109164
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsMice carrying the Fxntm1Pand allele were crossed with mice carrying the Meox2tm1(cre)Sor allele to remove the neomycin cassette, leaving an insertion of a GAA230 repeat expansion. (J:109164)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Fxn Mutation:  30 strains or lines available
References
Original:  J:109164 Miranda CJ, et al., Frataxin knockin mouse. FEBS Lett. 2002 Feb 13;512(1-3):291-7
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/10/2019
MGI 6.14
The Jackson Laboratory