Gas2l1^{tm1(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Gas2l1^{tm1(EUCOMM)Wtsi}
• Name: growth arrest-specific 2 like 1; targeted mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:4881081
• Gene: Gas2l1 Location: Chr11:5004132-5015327 bp, - strand Genetic Position: Chr11, 3.21 cM, cytoband A1
• IMPC: Gas2l1 gene page

Mutation origin

• Mutant Cell Lines: EPD0711_5_B03, EPD0711_5_B04, EPD0711_5_C03, EPD0711_5_E02, EPD0711_5_G02, EPD0711_5_G04, EPD0711_5_H03
• Germline Transmission: Unknown
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 2460 starting at position 5012083 and ending at position 5014543 of Chromosome 11 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. (J:155845, J:173534)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gas2l1 Mutation: 24 strains or lines available

References

• Original: J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010
• All: 2 reference(s)