Tg(IghAM14)#Mwg
Transgene Detail

Summary

• Symbol: Tg(IghAM14)#Mwg
• Name: transgene insertion, Martin Weigert
• MGI ID: MGI:4880702
• Synonyms: AM14VH
• Transgene: Tg(IghAM14)#Mwg Location: unknown
• Alliance: Tg(IghAM14)#Mwg page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(IghAM14)#Mwg expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Igh (MGI:96442)

• Mutation details: A rearranged VDJ genomic clone isolated from the hybridoma AM14 was used to create transgenic mice. Line 1 contains approximately 5-20 copies of the transgene. Line 2 was also produced from the same construct. The pound (#) symbol is used when no line is specified. (J:120857)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:118731 Lau CM, et al., RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. J Exp Med. 2005 Nov 7;202(9):1171-7
• All: 13 reference(s)