Kiss1tm1.1(cre)Uboe
Targeted Allele Detail
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Symbol: |
Kiss1tm1.1(cre)Uboe |
Name: |
KiSS-1 metastasis-suppressor; targeted mutation 1.1, Ulrich Boehm |
MGI ID: |
MGI:4878876 |
Synonyms: |
Kiss-Cre, KissIC, KissICneo- |
Gene: |
Kiss1 Location: Chr1:133254950-133257460 bp, + strand Genetic Position: Chr1, 57.91 cM
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Alliance: |
Kiss1tm1.1(cre)Uboe page
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Kiss1tm1.1(cre)Uboe expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: A targeting construct was used to insert an IRES-cre-FRT-pgk-neo-FRT cassette into the Kiss1 locus after exon 2. Properly targeted ES cell clones were injected into C57BL/6J blastcysts to produce KissICneo+ chimeras that were backcrossed to C57BL/6J animals. To remove the neo cassette, mice were bred to Flp deleter mice, then backcrossed to C57BL/6J for 6 generations.
(J:167285)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Kiss1
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Kiss1 Mutation: |
21 strains or lines available
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Original: |
J:167285 Mayer C, et al., Timing and completion of puberty in female mice depend on estrogen receptor alpha-signaling in kisspeptin neurons. Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22693-8 |
All: |
18 reference(s) |
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