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Mybboo
Chemically induced Allele Detail
Nomenclature
Symbol: Mybboo
Name: myeloblastosis oncogene; booreana
MGI ID: MGI:4867909
Gene: Myb  Location: Chr10:21124936-21160905 bp, - strand  Genetic Position: Chr10, 9.75 cM
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThis mutation was identified in a screen of ENU mutations for hematopoietic system phenotypes. An A to G transition was identified at position 923 in exon 8. This results in a Glutamic acid to Glycine change of amino acid residue 308 affecting the transactivation domain. (J:167270)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myb Mutation:  25 strains or lines available
References
Original:  J:167270 Papathanasiou P, et al., A recessive screen for genes regulating hematopoietic stem cells. Blood. 2010 Dec 23;116(26):5849-58
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory