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Vps26btm1Ktch
Targeted Allele Detail
Nomenclature
Symbol: Vps26btm1Ktch
Name: VPS26 retromer complex component B; targeted mutation 1, Kyu-Tae Chang
MGI ID: MGI:4867701
Gene: Vps26b  Location: Chr9:27004503-27030094 bp, - strand  Genetic Position: Chr9, 12.07 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:167062
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 5 and flanking intronic sequences were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:167062)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vps26b Mutation:  6 strains or lines available
References
Original:  J:167062 Kim E, et al., Implication of mouse Vps26b-Vps29-Vps35 retromer complex in sortilin trafficking. Biochem Biophys Res Commun. 2010 Dec 10;403(2):167-71
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory