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Crxtvrm65
Chemically induced Allele Detail
Nomenclature
Symbol: Crxtvrm65
Name: cone-rod homeobox; translational vision research model 65
MGI ID: MGI:4867395
Synonyms: Crx-L253X
Gene: Crx  Location: Chr7:15865947-15879955 bp, - strand  Genetic Position: Chr7, 8.6 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsA T-to-A nonsense mutation in the last exon of the gene is predicted to alter the leucine 277 residue to a termination codon in the encoded protein. This mutation affects both known isofoms. (J:166679)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Crx Mutation:  21 strains or lines available
References
Original:  J:166679 Won J, et al., Mouse model resources for vision research. J Ophthalmol. 2011;2011:391384
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/19/2020
MGI 6.15
The Jackson Laboratory