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Ednratm5Hku
Targeted Allele Detail
Nomenclature
Symbol: Ednratm5Hku
Name: endothelin receptor type A; targeted mutation 5, Hiroki Kurihara
MGI ID: MGI:4867385
Synonyms: EdnraEGFP
Gene: Ednra  Location: Chr8:77663029-77724452 bp, - strand  Genetic Position: Chr8, 36.63 cM, cytoband C2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:166932
Parent Cell Line:  ATOM1 (ES Cell)
Strain of Origin:  (C57BL/6 x 129)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, RMCE-ready, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsUsing recombination mediated cassette exchange (RCME) the neo cassette in Ednratm1Hku was replaced with an EGFP cassette and an FRT flanked puromycin cassette. (J:166932)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 33 assay results
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ednra Mutation:  7 strains or lines available
References
Original:  J:166932 Asai R, et al., Endothelin receptor type A expression defines a distinct cardiac subdomain within the heart field and is later implicated in chamber myocardium formation. Development. 2010 Nov;137(22):3823-33
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory