About   Help   FAQ
Gsk3btm1.2Ypc
Targeted Allele Detail
Nomenclature
Symbol: Gsk3btm1.2Ypc
Name: glycogen synthase kinase 3 beta; targeted mutation 1.2, YiPing Chen
MGI ID: MGI:4867289
Synonyms: Gsk3beta-
Gene: Gsk3b  Location: Chr16:38089001-38246084 bp, + strand  Genetic Position: Chr16, 26.54 cM, cytoband B4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:166721
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and second loxP site were inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette. Cre mediated recombination removed exon 2. (J:166721)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 21 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gsk3b Mutation:  96 strains or lines available
References
Original:  J:166721 He F, et al., Gsk3beta is required in the epithelium for palatal elevation in mice. Dev Dyn. 2010 Dec;239(12):3235-46
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory