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Dchs1tm1.2Irv
Targeted Allele Detail
Nomenclature
Symbol: Dchs1tm1.2Irv
Name: dachsous 1 (Drosophila); targeted mutation 1.2, Kenneth Irvine
MGI ID: MGI:4867020
Gene: Dchs1  Location: Chr7:105752990-105787654 bp, - strand  Genetic Position: Chr7, 55.98 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:169135
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was flanked by loxP sites and preceded by a 5' FRT-flanked PGK-neomycin cassette. Flp-mediated recombination removed the neo cassette, and cre-mediated recombination removed exon 2. (J:169135)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dchs1 Mutation:  61 strains or lines available
References
Original:  J:169135 Mao Y, et al., Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development. Development. 2011 Mar;138(5):947-57
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory