Tg(PSEN1)Dbo
Transgene Detail

Summary

• Symbol: Tg(PSEN1)Dbo
• Name: transgene insertion, David R Borchelt
• MGI ID: MGI:4849831
• Transgene: Tg(PSEN1)Dbo Location: unknown
• Alliance: Tg(PSEN1)Dbo page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(PSEN1)Dbo expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PSEN1 (5663)

  Psen1

  (MGI:1202717)

• Mutation details: The transgene consists of a mouse prion promoter and a cDNA encoding wild-type human presenilin 1. Transgene expression was verified by Northern and Western blot analysis of brain extracts derived from transgenic animals. Lines S8-4, R8-1, H8-4, and B8-1 were generated. The pound symbol (#) denotes when no single line is designated. (J:34323)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:80782 Borchelt DR, et al., A vector for expressing foreign genes in the brains and hearts of transgenic mice. Genet Anal. 1996 Dec;13(6):159-63
• All: 5 reference(s)