Tg(tetO-NR3C2)L1Frje
Transgene Detail
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| Symbol: |
Tg(tetO-NR3C2)L1Frje |
| Name: |
transgene insertion L1, Frederic Jaisser |
| MGI ID: |
MGI:4847948 |
| Synonyms: |
tetO-hMR |
| Transgene: |
Tg(tetO-NR3C2)L1Frje Location: unknown
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| Alliance: |
Tg(tetO-NR3C2)L1Frje page
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| Transgene Type: |
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Transgenic (Inducible, Inserted expressed sequence) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Mutation details: The AflII-XmaIII fragment of a human mineralocorticoid receptor cDNA (accession number NM_000901) from position 203 to 3198, including the full-length coding sequence, was blunt-ended and inserted into the EcoRV site located between the tetO promoter and the rabbit beta-globin polyadenylation sequence of the bidirectional tet-inducible pBI4 vector resulting in the tetO-hMR construct. Two founder lines were studied; in addition to line L1, line L2 was also produced.
(J:112171)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:112171 Ouvrard-Pascaud A, et al., Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias. Circulation. 2005 Jun 14;111(23):3025-33 |
| All: |
9 reference(s) |
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Analysis Tools
