Tg(GFAP-Ccl2)JE95Rmra
Transgene Detail

Summary

• Symbol: Tg(GFAP-Ccl2)JE95Rmra
• Name: transgene insertion JE95, Richard Ransohoff
• MGI ID: MGI:4843357
• Synonyms: huGFAP-CCL2hi tg+, huGFAP-MCP-1hi tg, huGFAP-MCP-1 tg+, JE-95, JE95
• Transgene: Tg(GFAP-Ccl2)JE95Rmra Location: unknown
• Alliance: Tg(GFAP-Ccl2)JE95Rmra page

Transgene origin

• Strain of Origin: (SWR/J x SJL/J)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(GFAP-Ccl2)JE95Rmra expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ccl2 (MGI:98259)

• Mutation details: The huGFAP-MCP-1 transgene was designed with the 2.2 kb promoter region from the human GFAP gene upstream of a mouse 1.7 kb mouse Ccl2 genomic DNA sequence. Line JE95 exhibited the highest expression level. (J:133880)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:133880 Huang D, et al., Pertussis toxin-induced reversible encephalopathy dependent on monocyte chemoattractant protein-1 overexpression in mice. J Neurosci. 2002 Dec 15;22(24):10633-42
• All: 3 reference(s)