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Pcid2tm1Imku
Targeted Allele Detail
Nomenclature
Symbol: Pcid2tm1Imku
Name: PCI domain containing 2; targeted mutation 1, Nobuo Sakaguchi
MGI ID: MGI:4843141
Gene: Pcid2  Location: Chr8:13077189-13105459 bp, - strand  Genetic Position: Chr8, 5.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:166080
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neomycin resistance gene was inserted in intron 1 and a third loxP sited was placed in the HindIII site 5' to exon 1. (J:166080)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pcid2 Mutation:  12 strains or lines available
References
Original:  J:166080 Nakaya T, et al., Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. J Immunol. 2010 Nov 1;185(9):5180-7
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/04/2020
MGI 6.14
The Jackson Laboratory