Lgals8tm1(KOMP)Vlcg
Targeted Allele Detail
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Symbol: |
Lgals8tm1(KOMP)Vlcg |
Name: |
lectin, galactose binding, soluble 8; targeted mutation 1, Velocigene |
MGI ID: |
MGI:4842980 |
Synonyms: |
Lgals8- |
Gene: |
Lgals8 Location: Chr13:12454296-12479825 bp, - strand Genetic Position: Chr13, 4.64 cM
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Alliance: |
Lgals8tm1(KOMP)Vlcg page
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IMPC: |
Lgals8 gene page |
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Lymphangiogenesis and severity of herpes simplex virus-induced keratitis and suture-induced inflammatory lymphangiogenesis is reduced in Lgals8tm1(KOMP)Vlcg/Lgals8tm1(KOMP)Vlcg mice
Show the 2 phenotype image(s) involving this allele.
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Mutant Cell Lines: |
14305A-F8, 14305C-B4 |
Germline Transmission: |
Earliest citation of germline transmission:
J:204812
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Parent Cell Line: |
VGB6 (ES Cell)
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Strain of Origin: |
C57BL/6NTac
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Project Collection: |
KOMP-Regeneron
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: ZEN-Ub1
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Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 18427bp between positions 12455667-12474093 of Chromosome 13 (Build GRCm39). Western blot analysis of liver tissue lysates confirmed the absence of protein expression in homozygous mutant mice.
(J:136110, J:235778)
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008; |
All: |
9 reference(s) |
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