Cyp2d37-ps^{tm1(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Cyp2d37-ps^{tm1(KOMP)Wtsi}
• Name: cytochrome P450, family 2, subfamily d, polypeptide 37, pseudogene; targeted mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:4841322
• Gene: Cyp2d37-ps Location: Chr15:82572951-82574259 bp, - strand Genetic Position: Chr15, 38.68 cM
• IMPC: Cyp2d37-ps gene page

Mutation origin

• Mutant Cell Line: EPD0451_3_H03
• Germline Transmission: Unknown
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 675 starting at position 82573792 and ending at position 82574467 of Chromosome 15 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. (J:148605, J:173534)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Cyp2d37-ps Mutation: 9 strains or lines available

References

• Original: J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009
• All: 2 reference(s)