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Targeted Allele Detail
Symbol: Cc2d1atm1a(KOMP)Mbp
Name: coiled-coil and C2 domain containing 1A; targeted mutation 1a, Mouse Biology Program, UCDavis
MGI ID: MGI:4840725
Synonyms: TAPE-
Gene: Cc2d1a  Location: Chr8:84132828-84147936 bp, - strand  Genetic Position: Chr8, 40.32 cM
Mutant Cell Lines:  DEPD00533_1_A06, DEPD00533_1_A08, DEPD00533_1_C06, DEPD00533_1_D07, DEPD00533_1_E08, DEPD00533_1_F06, DEPD00533_1_F07, DEPD00533_1_G06, DEPD00533_1_H06
Germline Transmission:  Earliest citation of germline transmission: J:190401
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_Bact_P
Mutation detailsThe L1L2_Bact_P cassette was inserted at position 84139851 of Chromosome 8 upstream of the critical exon(s) (Build GRCm38). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon(s) at position 84138197. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other KOMP alleles can be found at http://www.knockoutmouse.org/aboutkompstrategies. (J:157064, J:190401)
Generation of the Cc2d1atm1a(KOMP)Mbp allele
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Cc2d1a Mutation:  18 strains or lines available
Original:  J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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