About   Help   FAQ
Cthtm1Iish
Targeted Allele Detail
Nomenclature
Symbol: Cthtm1Iish
Name: cystathionase (cystathionine gamma-lyase); targeted mutation 1, Isao Ishii
MGI ID: MGI:4840236
Synonyms: CSE-KO
Gene: Cth  Location: Chr3:157894248-157925077 bp, - strand  Genetic Position: Chr3, 81.55 cM
Proximal muscle atrophy in Cthtm1Iish/Cthtm1Iish mice fed a low cysteine diet

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:166184
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Generation of the Cthtm1Iish allele
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cth Mutation:  11 strains or lines available
References
Original:  J:166184 Ishii I, et al., Cystathionine gamma-Lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury. J Biol Chem. 2010 Aug 20;285(34):26358-68
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/19/2014
MGI 5.19
The Jackson Laboratory