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Targeted Allele Detail
Symbol: Hprttm1(tetO-Runx1,-EGFP)Enk
Name: hypoxanthine guanine phosphoribosyl transferase; targeted mutation 1, Elena N Kozlova
MGI ID: MGI:4840037
Synonyms: HPRT-Runx1a-IRES-EGFP
Gene: Hprt  Location: ChrX:52988137-53021659 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Germline Transmission:  Earliest citation of germline transmission: J:165939
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Inducible, Inserted expressed sequence, Reporter)
Mutation:    Insertion
Hprttm1(tetO-Runx1,-EGFP)Enk expresses 1 gene
Mutation detailsA cassette containing the tetracycline-responsive element (TRE) driving inducible expression of the mouse cDNA and an IRES/EGFP were inserted into the locus. (J:165939)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt Mutation:  31 strains or lines available
Original:  J:165939 Kanaykina N, et al., In vitro and in vivo effects on neural crest stem cell differentiation by conditional activation of Runx1 short isoform and its effect on neuropathic pain behavior. Ups J Med Sci. 2010 Feb;115(1):56-64
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
The Jackson Laboratory