Tg(Emu-ETV6/JAK2)#Ghy
Transgene Detail
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| Symbol: |
Tg(Emu-ETV6/JAK2)#Ghy |
| Name: |
transgene insertion, Jacques Ghysdael |
| MGI ID: |
MGI:4840013 |
| Synonyms: |
EmuSRa-TEL-JAK2 |
| Transgene: |
Tg(Emu-ETV6/JAK2)#Ghy Location: unknown
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| Alliance: |
Tg(Emu-ETV6/JAK2)#Ghy page
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| Strain of Origin: |
C57BL/6 x DBA/2
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: A cDNA encoding an HA-tagged version of the TEL-JAK2 protein
encoded by a fusion gene, identified in a case of acute
lymphoblastic T-cell leukemia, was inserted downstream of the
Emu/SRalpha promoter/enhancer construct. The Emu/SRalpha enhancer/promoter allows high-level specific expression in lymphoid cells but only low to undetectable expression in nonlymphoid tissues.
(J:166206)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:166206 Carron C, et al., TEL-JAK2 transgenic mice develop T-cell leukemia. Blood. 2000 Jun 15;95(12):3891-9 |
| All: |
3 reference(s) |
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Analysis Tools
