Tg(GATA3-EGFP)1Smal
Transgene Detail

Summary

• Symbol: Tg(GATA3-EGFP)1Smal
• Name: transgene insertion 1, Stavros Malas
• MGI ID: MGI:4838415
• Synonyms: GATA3^-eGFP
• Transgene: Tg(GATA3-EGFP)1Smal Location: unknown
• Alliance: Tg(GATA3-EGFP)1Smal page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: A BAC containing the GATA3 locus was engineered so that the first exon of the gene was replaced with the coding sequence for EGFP. An frt-flanked kanamycin resistance gene driven by the prokaryotic EM7 promoter was used for selection of correctly recombined colonies. The selection cassette was subsequently removed by flp recombinase in bacteria. The 180 kb final BAC was injected into pronuclei, generating four founder lines. One line was selcected for further analysis. No line numbers were specified in the reference. (J:164670)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:164670 Panayi H, et al., Sox1 is required for the specification of a novel p2-derived interneuron subtype in the mouse ventral spinal cord. J Neurosci. 2010 Sep 15;30(37):12274-80
• All: 3 reference(s)