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Rbfox1tm1.1Dblk
Targeted Allele Detail
Nomenclature
Symbol: Rbfox1tm1.1Dblk
Name: RNA binding protein, fox-1 homolog (C. elegans) 1; targeted mutation 1.1, Douglas Black
MGI ID: MGI:4838179
Synonyms: Fox-1flox, Rbfox1loxP
Gene: Rbfox1  Location: Chr16:5885355-7411526 bp, + strand  Genetic Position: Chr16, 3.34 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:165698
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert loxP sites flanking exons 11-12 of the RNA binding protein, fox-1 homolog 1 (Rbfox1) gene, followed by a frt-flanked neomycin resistance (neo) cassette. Flp-mediated recombination removed the neo cassette leaving exons 11 and 12 floxed. (J:165698)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rbfox1 Mutation:  19 strains or lines available
References
Original:  J:165698 Black D, Direct Data Submission 2010/11/09. MGI Direct Data Submission. 2010;
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory